1,2,4-oxadiazole derivatives as hPPAR alpha agonists

Details 1,2,4-oxadiazole derivatives as hPPAR alpha agonists 1,2,4-oxadiazole derivatives as hPPAR alpha agonists

2006-11-28

2006-11-28

Shameem, Golam M. M. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S125000, C548S131000, C514S361000

Reexamination Certificate

active

07141591

ABSTRACT:
A compound of formula (I) and pharmaceutically acceptable salts, solvates and hydrolysable esters thereof wherein: X1is O or S; X2is O or S; n is 1–3, One of Y and Z is N, and the other is O; R1and R2are independently halogen, H, CH3, OCH3or C1-3alkyl; Each R3independently is halogen, CF3, C1-6straight or branched alkyl; R4and R5are independently H or C1-3alkyl. y is 0, 1, 2, 3, 4 or 5.

REFERENCES:
patent: 6306873 (2001-10-01), Burns et al.
patent: 6875780 (2005-04-01), Auerbach et al.
patent: 6964983 (2005-11-01), Auerbach et al.
patent: WO/00/64876 (2000-11-01), None
patent: WO/01/16120 (2001-03-01), None

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