1,2,4-oxadiazol-5-one-4-(benzimidazolylmethylamino)benzamidi...

Details 1,2,4-oxadiazol-5-one-4-(benzimidazolylmethylamino)benzamidi... 1,2,4-oxadiazol-5-one-4-(benzimidazolylmethylamino)benzamidi...

2007-03-02

2008-12-02

Shiao, Rei-tsang (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S304700, C546S273400

Reexamination Certificate

active

07459566

ABSTRACT:
A process for preparing an optionally substituted 4-benzimidazol-2-ylmethylamino)benzamidine, the process comprising:(a) condensing an optionally suitably substituted diaminobenzene with 2-[4-(1,2,4-oxadiazol-5-on-3-yl)phenylamino]acetic acid;(b) hydrogenating the product obtained from step (a); and(c) optionally carboxylating the amidino group of the product obtained from step (b).

REFERENCES:
patent: 6248770 (2001-06-01), Ries et al.
patent: 6414008 (2002-07-01), Hauel et al.
patent: 6451832 (2002-09-01), Ries et al.
patent: 6455529 (2002-09-01), Gante et al.
patent: 6593355 (2003-07-01), Ries et al.
patent: 763094 (2000-01-01), None
patent: 199 62 329 (2001-06-01), None
patent: WO 00/01704 (2000-01-01), None
Abstract of WO 2005-EP2881, Boeckel et al. and STN search report.
N-tosylation of amine and alcohol, on-line PDF file from www.chm.davidson.edu/erstevens/202lab1.pdf.
Abstract for DE 199 62 329 A1.

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