Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-09-09
2011-12-13
Hui, San-Ming (Department: 1628)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S594000
Reexamination Certificate
active
08076325
ABSTRACT:
Compounds of formula (I):wherein:R1represents a hydrogen atom or a group selected from cycloalkyl, benzyl and optionally substituted alkyl,R2, R3, R4and R5each represent a hydrogen atom or a hydroxy, methyl, —OSO2R10, —OCOR10or optionally substituted alkoxy group, or R2and R3, or R3and R4, or R4and R5together form a group —O—(CH2)q—O—, —O—CH═CH—O— or —O—CH═CH—,R6, R7, R8and R9each represent a hydrogen atom or an alkoxy group, or R6and R7, or R7and R8, or R8and R9together form a group —O—(CH2)q—O—,R10represents a group selected from linear or branched C1-C6alkoxy, NR11R′11and optionally substituted alkyl,R11and R′11each represent a hydrogen atom or an alkyl group, or R11and R′11together with the nitrogen atom carrying them form an optionally substituted, monocyclic or bicyclic, nitrogen-containing heterocycle,X represents O, NH or CH2,m and p each represent 0 or 1,n and q each represent 1 or 2,in racemic form or in the form of optical isomers, and also addition salts thereof with a pharmaceutically acceptable acid.Medicinal products containing the same which are useful in treating various pathologies.
REFERENCES:
patent: 4584293 (1986-04-01), Reiffen et al.
patent: 6514964 (2003-02-01), Chen et al.
patent: 0161604 (1985-11-01), None
patent: 0534859 (1993-03-01), None
patent: 2006/092491 (2006-09-01), None
Wickenden AD, Maher MP, Chaplan SR. HCN Pacemaker Channels and Pain: A Drug Discovery Perspective. Current Pharmaceutical Design. Jun. 2009: 15(6); 2149-2168.
French Preliminary Search Report for FR/0706346 of May 6, 2008.
Kannel, et al.,American Heart Journal, 1987, 113, 1489-1494.
Borer, et al.,Circulation, 2003, 107, 817-823.
Diaz, et al.,European Heart Journal, 2005, 26, 967-974.
Hjalmarson, et al.,American Journal of Cardiology, 1990, 65, 547-553.
Mulder, et al.,Circulation, 2004, 109, 1674-1679.
Beere, et al.,Science, 1984, 226, 180-182.
Heidland, et al.,Circulation, 2001, 104, 1477-1482.
Caignard Pascal
Chimenti Stefano
Dessinges Aimee
Goument Bertrand
Peglion Jean-Louis
Hueschen and Sage
Hui San-Ming
Les Laboratoires Servier
Zarek Paul
LandOfFree
1,2,4,5-tetrahydro-3H-benzazepine compounds, a process for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1,2,4,5-tetrahydro-3H-benzazepine compounds, a process for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2,4,5-tetrahydro-3H-benzazepine compounds, a process for... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4262458