Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-06-22
1990-12-11
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540557, 540567, 544345, 544356, 544354, 548178, 548126, 548255, 548261, 549 57, C07D48704, C07D51304, C07D49504, A61K 31495
Patent
active
049771558
ABSTRACT:
Heterocyclic dihydroxyquinoxaline compounds having the formula ##STR1## wherein R.sup.2 is hydrogen, NO.sub.2, NH.sub.2, CN, halogen, or SO.sub.2 NH.sub.2 ; --X--Y--Z-- is selected from --N.dbd.N--N.sup.3 --,--NR.sup.3 --N.dbd.N--,.dbd.N--NR.sup.3 --N.dbd., wherein R.sup.3 is hydrogen, lower alkyl, or CF.sub.3.
The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use.
The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters.
REFERENCES:
patent: 4912108 (1990-03-01), Jacobsen
Drejer Jorgen
Honore Tage
Jacobsen Poul
Nielsen Flemming E.
A/S Ferrosan
Berch Mark L.
Hueschen Gordon W.
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