1,2,3-triazole anticonvulsant drugs

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514359, 546276, 548255, C07D40104, A61K 3141

Patent

active

046109943

ABSTRACT:
Anticonvulsant compositions comprise as the active ingredient a compound selected from the group consisting of those of the formulae: ##STR1## wherein R.sub.1 is phenyl, 4-pyridyl, 3-pyridyl, or 2-pyridyl, and R.sub.2 is hydrogen, m- or p-methyl, p-methoxy, m- or p-chloro, m- or p-bromo, m- or p-fluoro, m- or p-trifluoromethyl, 3,4-dichloro or 3,5-dichloro. The compositions are administered to mammals in an amount to provide a dosage amount ranging from about 25 mg/kg to 300 mg/kg.

REFERENCES:
patent: 3470196 (1969-09-01), Harvey
patent: 4013441 (1977-03-01), Bianchetti et al.
patent: 4474599 (1984-10-01), Rogers et al.
Kadaba, Synthesis, Sep. 1978, pp. 694-695.
Kadaba, Jour. F. Prakt Chemie., Band 324, Heft 5, 1982, S. 857-864.

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