1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS d

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514310, 546143, 546146, 546147, A61H 3147, C07D21716

Patent

active

052369340

ABSTRACT:
Provided are 1,2,3,4-tetrahydroisoquinolines, methods for preparing them, pharmaceutical compositions containing them, and methods of using them to treat disorders of mammals mediated by AT.sub.2 receptors in the central nervous system.

REFERENCES:
patent: 4344949 (1982-08-01), Hoefla et al.
patent: 4812462 (1989-03-01), Blankely et al.
patent: 5059608 (1991-10-01), Takasugi et al.
patent: 5091390 (1992-02-01), Ardecky et al.
Niopas, "Pharm. Delt., Epistem. Ekdosis", vol. 10, No. 1, 1984, pp. 1-15.
"Chemical Abstracts" version vol. 104, 1986, p. 688.

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