1,2,3,4-tetrahydro-8-quinolinol derivatives and anti-allergic us

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546165, 546166, 546179, C07D21336, A61K 3147

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active

048430820

ABSTRACT:
Leukotriene biosynthesis in macrophage cells is inhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.1 and R.sub.2 are each hydrogen and R.sub.3 is alkyl or arylalkyl;

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Chemical Abstracts, vol. 96, 159, 165m-"Spectrum of action of synthetic 8-oxyquinoline derivatives".
Indian Journal of Chemistry, vol. 12, pp. 252-257, 1974, "Condensed Heterotricycles*: Synthesis of Pyridine-annealed Dibenz[b,f][I,4]-oxazepines", Nagarajan et al.
Journal of American Chemical Society, vol. 89, pp. 3607-3612, 1967, "On Cobaloximes with Cobalt-Sulfur Bonds and Some Model Studies Related to Cobamide-Dependent Methyl-Group-Transfer Reactions", Schrauzer et al.

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