1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphth

Details 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphth 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphth

1976-04-22

1978-12-19

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544378, 544392, 544394, A61K 31495, C07D29508

Patent

active

041306465

ABSTRACT:
Compounds having the structure ##STR1## and pharmaceutically acceptible salts thereof, wherein R.sub.1 is hydrogen, halogen, hydroxy, alkanoyloxy, alkoxy, alkylthio, alkyl, trifluoromethyl or methylenedioxy; R.sub.2 is hydrogen, halogen, alkyl, alkoxy, alkylthio, or trifluoromethyl; R.sub.3 is formyl or alkanoyl; m is 1 or 2; and n is 0, 1 or 2, have useful sedative and muscle relaxant activity, and can be used as tranquilizers.

REFERENCES:
patent: 3146235 (1964-08-01), Nichols
patent: 3547923 (1970-12-01), Standridge et al.
patent: 3729474 (1973-04-01), Mentrup et al.
patent: 3845058 (1974-10-01), Lembo et al.
patent: 3886168 (1975-05-01), Himmele et al.
patent: 3919230 (1975-11-01), Hill et al.
patent: 4022791 (1977-05-01), Welch
Eirin et al., Eur. J. Med. Chem.-Chimica Therapeutica, 11 (1) pp. 29-32 (1976).

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