1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing...

Details 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing... 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing...

2006-04-18

2006-04-18

Coleman, Brenda (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C424S001650, C424S001810, C424S009300, C424S009440, C540S580000

Reexamination Certificate

active

07030109

ABSTRACT:
The present invention discloses radioligands of 9-arylsulfone of the formula (X)or a pharmaceutically acceptable salt or enantiomer thereof, which are useful in diagnosing depression, obesity and other CNS disorders.

REFERENCES:
patent: 3576872 (1971-04-01), Singhal
patent: 3652588 (1972-03-01), Hester, Jr.
patent: 3676558 (1972-07-01), Hester, Jr.
patent: 3839357 (1974-10-01), Hester, Jr.
patent: 3914418 (1975-10-01), Patchett et al.
patent: 3948987 (1976-04-01), Fridinger
patent: 4026830 (1977-05-01), Gillman et al.
patent: 4239888 (1980-12-01), Miller
patent: 4298676 (1981-11-01), Barton et al.
patent: 4332820 (1982-06-01), Markley
patent: 4894358 (1990-01-01), Filosa et al.
patent: 5534518 (1996-07-01), Henrie, II et al.
patent: 5952349 (1999-09-01), Asberom et al.
patent: 619 460 (1980-09-01), None
patent: 149 525 (1973-07-01), None
patent: 229 033 (1984-05-01), None
patent: 21 20 708 (1972-11-01), None
patent: 24 38 099 (1976-02-01), None
patent: 24 38 120 (1976-02-01), None
patent: 25 09 037 (1976-09-01), None
patent: 25 48 910 (1977-05-01), None
patent: 27 07 784 (1977-08-01), None
patent: 27 48 978 (1979-05-01), None
patent: 30 27 530 (1982-02-01), None
patent: 38 31 445 (1990-03-01), None
patent: 196 54 445 (1998-07-01), None
patent: 198 29 357 (2000-01-01), None
patent: 0 013 414 (1980-07-01), None
patent: 0 017 883 (1980-10-01), None
patent: 0 028 381 (1981-05-01), None
patent: 0 035 712 (1981-09-01), None
patent: 0 102 476 (1984-03-01), None
patent: 0 282 448 (1988-09-01), None
patent: 0354 303 (1990-02-01), None
patent: 0 524 781 (1993-01-01), None
patent: 666 253 (1995-08-01), None
patent: 0 930 302 (1999-07-01), None
patent: 1 489 916 (1967-11-01), None
patent: 6 699 (1969-02-01), None
patent: 2 053 028 (1971-04-01), None
patent: 2 110 283 (1972-06-01), None
patent: 2 135 740 (1972-12-01), None
patent: 2 154 568 (1973-05-01), None
patent: 2 230 354 (1974-12-01), None
patent: 1 499 717 (1996-11-01), None
patent: 1293540 (1972-10-01), None
patent: 02 048564 (1980-02-01), None
patent: 60 044557 (1985-03-01), None
patent: 3056431 (1991-03-01), None
patent: 436 817 (1974-07-01), None
patent: 380644 (1973-05-01), None
patent: 475382 (1975-06-01), None
patent: WO94/18980 (1994-09-01), None
patent: WO97/13748 (1997-04-01), None
patent: WO99/32463 (1999-07-01), None
patent: WO99/44618 (1999-09-01), None
patent: WO 99/62506 (1999-12-01), None
patent: 6 801 404 1 (1968-08-01), None
patent: 7 603 751 (1978-02-01), None
(Abstract) XP-002150015—J. Med. Chem. (1969), 12, 709-11. Antimalarial compounds related to diaminodiphenyl sulfone; Henry Bader, et al.
(Abstract) XP-002150014 -Macromolecules (1988), 21 (8), 2644-7 A novel route to polypyrazoles; James A. Moore, et al.
(Abstract) XP-002150013—Khim. Geterotsikl. Soedin. (1991), (1) 54-6 Synthesis of 5-[(p-chlorophenyl) sulfonyl]indoles; N.T. Mirziashvili, et al.
(Abstract) XP-002150011—J. Chem. Eng. Data (1966), 11(4), 612-14; o-Trifluoromethylthiophenol and its derivatives; N. Sharghi, et al.
(Abstract) XP-002150010—Synthesis (1971), (7), 372-4; Aminoaryl sulfones. New preparation procedure; Everett E. Gilbert.
(Abstract) XP-002150009—J. Med. Chem. (1971), 14(12), 1166-9; Antimalarial agents. 8. Ring-substituted bis (4-aminophenyl) sulfones and their precursors; Ivan C. Popoff, et al.
(Abstract) XP-002150008—ZH. Prikl. Khim. (Leningrad) (1972), 45(12), 2704-10, Synthesis of som substituted diphenyl sulfones; I.V. Budnii, et al.
(Abstract) XP002150007—J. Mol. Struct. (1973), 16(2), 299-306, NMR data and conformational preference of o-substituted diph nyl sulfones; G. Montaudo, et al.
(Abstract) XP002150005—ZH., Khim. 1973; TR. Vses. Nauch-issled. Proekt. Inst. Monomerov (1972), 3(3), 75-80; Synthesis of 3,4,4′-triaminodipheny sulfones and their use in modifying heat-stable fibers; A. V. Ivanov, et al.
(Abstract) XP002150003—Acta Cienc. Indica (1977), 3(1), 18-19; Fries rearrangement of N-benzenesulfonylaniline; C. Srinivasan.
(Abstract) XP002150002—Khim. Geterotsikl. Soedin (1979), (7) 968-71; Synthesis and study of some bis (1′, 8′-naphthoylene-1,2-benzimidazoles); A.L. Rusanov, et al.
(Abstract) XP002150001—Katalitich. Prevrashcheniya Organ. Soedin., Perm (1978) 20-5; Sulfarylation of p-substituted benzenesulfonic acid salts rin phosphoric acid; A. G. Klein, et al.
(Abstract) XP00215000—Quant. Struct.-Act. Relat. (1987), 6(4), 164-72; Multiple regression analysis of antimalarial activities of sulfones and sulfonamides in cell-free systems and principal component analysis to compare with antibacterial activities; M. Wiese, et al.
(Abstract) XP002149999—J. Med. Chem. (1989), 32(10), 2396-9; Quantitative structure-activity relationships in dihydropteroate synthase inhibition by multisubstituted sulfones. Design and synthesis of some new derivatives with improved potency; G. Pier De Benedetti, et al.
(Abstract) XP002149998—Arzneim.-Forsch. (1989), 39(9), 1081-4; Studies on 2,3,N,N′-substituted 4,4′-diaminodiphenylsulfones as potential antimalarian agents; M. Saxena, et al.
(Abstract) XP002149997—J. Clin. Invest. (1990), 85(2), 371-9; Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase; Carmen J. Allegra, et al.
(Abstract) XP002149996—Theochem (1992), 88, 231-48; Electrostatics in quantitative structure-activity relationship analysis; P.G. De Benedetti.
(Abstract) XP002149995—J. Chem.Soc., Kerkin Trans. 1 (1992), (22), 3129-34; 2H-Benzimidazoles (isobenzimidazoles). Brian Iddon, et al.
(Abstract) XP002149994—Boll. Chim. Farm. (1994), 133(2), 72-5; Synthesis and antimicrobial evaluation of new derivatives of diphenylsulfone; A. De La Cruz, et al.
(Abstract) XP002149993—Environ. Toxicol. Pharmacol (1998) 5(2), 145-153; The effect of 2,2′-substitution on the metabolism and toxicity of dapsone in vitro and in vivo; M.D. Tingle, et al.
(Abstract) XP002149992—Bol. Soc. Chil. Quim (2000), 45(2), 181-189; Synthesis characterization and electrical properties of poly (p-phenylsulfonyl aniline); Fernando R. Diaz, et al.
(Abstract) XP002149991—Indian J. Appl. Chem. (1966), 29(2-3), 51-3; Potential fungicidal compounds. IV. Some aryl polynitrophenyl sulfones; Satya Prakash Gupta, et al.
(Abstract) XP002149990—J. Chem. Soc. C. (1968), (3), 322-7; Photochemical transformations. XXII. Reactions of 2,4-dinitrobenzenesulfenyl derivatives; Derek H. R. Barton, et al.
(Abstract) XP002149989—ZH. Fiz, Khim. (1968), 42(8), 1861-4; Interaction of functional groups through.pi.-electron systems. V. Interaction through aromatic rings connected by a monofunctional bridging group; A.E. Lutskii, et al.
(Abstract) XP002149987—Ann. Soc. Sci. Bruxelles, Ser. 1, (1969); New ph nothiazines by Smiles arrangement; R.L. Mital, et al.
(Abstract) XP002149986—J. Chem. Soc., Perkin Trans. 1 (1973), (18), 1980-3; .sigma.-Complex formulation and aromatic substitution with thiolates and nitroatyl thio ethers; Gino Biggi, et al.
(Abstract) XP-002149983—J. Org. Chem. 1975, 40(25), 3777-8; Electronic and steric effects in nucleophilic aromatic substitution. Kinetic studies on the reactions between ethers and thioethers of 2,4-dinitrophenol and nucleophiles; G. Bartoli, et al.
(Abstract) XP002149981—Chim. Acta. Turc. (1981), 9(2), 395-9; Synthesis and fungitoxicity of some substituted aryl polynitrophenyl sulfies and sulfones; Merra Katiyar, et al.
(Abstract) XP002149979—Khim. Geterotsikl. Soedin. (1968), (1), 131-6; Indole derivatives. XXIV. Synthesis of some 1,2,3,4,5,6-hexahydroazepino [4,5-b]indoles; N.M. Sharkova, et al.
(Abstract) XP002149978—Farmakol. Toksikol (Moscow), (1972), 35(3), 274-80; Pharmacological activity spectra of some azepino-and benzoxepinoindole derivatives; G. N. Artemenko, et al.
XP000650781—Journal of Medicinal Chemistry, US, American Chemical Society, Washington. vol. 11, No. 1, 1968, pp. 101-106; Azepinoindoles. I. Hexahydroazepino[4,5-b]indoles; J. B. He

Affiliated with

Also associated with

Rating

1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3586551