1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocines

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424267, 424DIG13, C07D22126

Patent

active

041056590

ABSTRACT:
1,2,3,4,5,6-Hexahydro-3-lower alkenyl-6-(R.sup.1)-11-(R.sup.2)-8-hydroxy-2,6-methano-3-benzazocines, wherein R.sup.1 and R.sup.2 are hydrogen or lower alkyl, and certain ethers and esters thereof, are obtained from analogous 3-unsubstituted compounds. The products have pharmacodynamic activity and are useful as antagonists of strong analgesic agents, such as morphine and meperidine, and are useful in humans as agents for producing analgesia.

REFERENCES:
patent: 3250678 (1966-05-01), Archer
patent: 3723440 (1973-03-01), Freter et al.

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