Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1964-02-05
1978-08-08
Randolph, John D.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424267, 424DIG13, C07D22126
Patent
active
041056590
ABSTRACT:
1,2,3,4,5,6-Hexahydro-3-lower alkenyl-6-(R.sup.1)-11-(R.sup.2)-8-hydroxy-2,6-methano-3-benzazocines, wherein R.sup.1 and R.sup.2 are hydrogen or lower alkyl, and certain ethers and esters thereof, are obtained from analogous 3-unsubstituted compounds. The products have pharmacodynamic activity and are useful as antagonists of strong analgesic agents, such as morphine and meperidine, and are useful in humans as agents for producing analgesia.
REFERENCES:
patent: 3250678 (1966-05-01), Archer
patent: 3723440 (1973-03-01), Freter et al.
Randolph John D.
Sterling Drug Inc.
Wyatt B. Woodrow
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