1,2,3,4,5,6-Hexahydro-1,6-methano-3-benzazocines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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260239BB, 2603405, 2603407, A61K 3155, C07D22332

Patent

active

041653718

ABSTRACT:
1,2,3,4,5,6-Hexahydro-1,6-methano-3-benzazocines and derivatives thereof are described together with intermediates and methods for their preparation and pharmaceutical compositions and methods for the use thereof. Representative compounds of this new ring system exhibit useful analgesic activity without either physical dependence liability or narcotic antagonist properties.

REFERENCES:
patent: 3294817 (1966-12-01), Sallay
patent: 3516987 (1970-06-01), Koo et al.
patent: 3686167 (1972-08-01), Fujimura et al.
Takeda et al., "Journal of Med. Chem", vol. 13 #4, 1970, pp. 630-634.

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