1,2,3,4,4a,9b-Hexahydro-4a-piperazinylmethyl-4-dibenzofuranone o

Details 1,2,3,4,4a,9b-Hexahydro-4a-piperazinylmethyl-4-dibenzofuranone o 1,2,3,4,4a,9b-Hexahydro-4a-piperazinylmethyl-4-dibenzofuranone o

1982-06-09

1983-10-11

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544360, 544375, 549460, 549461, A61K 31495, C07D40500, C07D40506, C07D30781

Patent

active

044092210

ABSTRACT:
The present invention is dealing with compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, in which R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are identical or different and represent hydrogen, halogen, lower alkyl or alkoxy or trifluoromethyl; R.sub.5 represents hydrogen or lower alkyl, X represents hydrogen and Y represents hydroxy, or X and Y together represent oxygen and Ar represents an optionally substituted aromatic moiety, having potent anti-bronchoconstrictor properties.

REFERENCES:
patent: 3317527 (1967-05-01), Skaletzky
patent: 3337563 (1967-08-01), Skaletzky
patent: 3496181 (1970-02-01), Skaletzky

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