1,2,3,4,10,19-Hexanor-9-oxo-5,9-seco-25D-spirostan-5-oic acid

Details 1,2,3,4,10,19-Hexanor-9-oxo-5,9-seco-25D-spirostan-5-oic acid 1,2,3,4,10,19-Hexanor-9-oxo-5,9-seco-25D-spirostan-5-oic acid

1976-03-09

1977-03-29

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603432S, 2603459, 195 51R, 195 51E, C07D30922

Patent

active

RE0291633

ABSTRACT:
The spirostan derivative 1,2,3,4,10,19-hexanor-[5] 9-oxo-5,9-seco-25D-spirostan-5-oic acid is obtained by the microbiological degradation of diosgenin utilizing Proactinomyces restrictus Turfitt CBS 157.45 or enzymes derived therefrom. The aforesaid spirostan derivative is useful as an intermediate in the synthesis of medicinally valuable 9.beta.,10.alpha.-steroids and norsteroids.

REFERENCES:
patent: 3068244 (1962-12-01), Zderic
patent: 3102892 (1963-09-01), Zderic

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