1,2(1,4)-dimethyl-4(2)-(2-hydroxyethyl)-5-nitro-imidazole antipr

Details 1,2(1,4)-dimethyl-4(2)-(2-hydroxyethyl)-5-nitro-imidazole antipr 1,2(1,4)-dimethyl-4(2)-(2-hydroxyethyl)-5-nitro-imidazole antipr

1984-12-24

1987-07-07

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548339, A61K 31415, C07D23394

Patent

active

046787992

ABSTRACT:
A group of 4-substituted-5-nitroimidazoles is described, having effective antiprotozoal activity with much less mutagenicity than is shown by known 5-nitroimidazoles.

REFERENCES:
patent: 3646027 (1972-02-01), Carlson et al.
Maron et al., 113 Mutation Research, pp. 173-215, (1983).
Bradley et al., 42 Cancer Research, pp. 2592-2597, (1982).
Miwa et al., Biological Reactive Intermediates III, Kacsis (Edit.), pp. 527-535 (1986).
Goldman, The Johns Hopkins Medical J., 147, pp. 1-9, (1980).
Robbie et al., J. Obstet. Gynecol., 145, pp. 865-881 (1983).
Miwa et al., Chem. Biol. Interactions, 50, pp. 189-202 (1984).
McCann et al., Proc. Nat. Acad. Sci. USA, 72, 5135-5139 (1975).

Affiliated with

Also associated with

Rating

1,2(1,4)-dimethyl-4(2)-(2-hydroxyethyl)-5-nitro-imidazole antipr does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,2(1,4)-dimethyl-4(2)-(2-hydroxyethyl)-5-nitro-imidazole antipr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2(1,4)-dimethyl-4(2)-(2-hydroxyethyl)-5-nitro-imidazole antipr will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1663157