(1,10b-dihydro-2-(aminoalkyl-phenyl)-5H-pyrazolo[1,5...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S095000

Reexamination Certificate

active

07745432

ABSTRACT:
The present invention relates to 5H-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as inhibitors of the viral replication of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present HIV inhibitors with other anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS.

REFERENCES:
patent: 0 499 299 (1992-08-01), None
patent: 0 563 733 (1993-10-01), None
patent: 0 721 331 (1996-07-01), None
patent: 1 359 147 (2003-11-01), None
patent: WO 94/05263 (1994-03-01), None
patent: WO 97/44014 (1997-11-01), None
patent: WO 01/22938 (2001-04-01), None
American College of Rheumatology, downloaded on Jul. 29, 2009: http://www.rheumatology.org/public/factsheets/diseases—and—conditions/HIV.asp?aud=.
Cross et al., “IUPAC Commission on Nomenclature of Organic Chemistry—Rules for the Nomenclature of Organic Chemistry, Section E: Stereochemistry (Recommendations 1974),”Pure&Appl. Chem., 1976; 45:11-30.
De Meester et al., “The Oxidation of 6- and 7-Aryl-4(3H)-pteridinones by Immobilized Arthrobacter M-4 Cells Containing Xanthine Oxidase [1],”J. Het. Chem., 1987; 24:, 441-451.
Gu et al., “Design, Synthesis, and Monoamine Transporter Binding Site Affinities of Methoxy Derivatives of Indatraline,”J. Med. Chem., 2000; 43:4868-4876.
Orlov V D et al., “Substituted 1,10b-Dihydro-5H-Pyrazolo[1,5-c]-1,3-Benzoxazines,”Chemistry of Heterocyclic Compounds(A Translation of Khimiya Geterotsiklicheskikh Soedinenti), 1991; 27(8):910-914.
Reddy et al., “Synthesis and Antimicrobial Activity of Some New Bis(2-pyrazolino-3-yl)benzenes,”J. Ind. Chem. Soc., 1989; 66:893-896.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

(1,10b-dihydro-2-(aminoalkyl-phenyl)-5H-pyrazolo[1,5... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with (1,10b-dihydro-2-(aminoalkyl-phenyl)-5H-pyrazolo[1,5..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and (1,10b-dihydro-2-(aminoalkyl-phenyl)-5H-pyrazolo[1,5... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4231673

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.