1,10[8,9-Benz]phenanthroline

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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427258, C07D47104

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active

044749619

ABSTRACT:
Compounds represented by the general formula (I) ##STR1## in which R represents an aniline substituted in the para position by either --NHSO.sub.2 CH.sub.3 or --NHCOOCH.sub.3 and bearing either an --H or --OCH.sub.3 in the ortho position, or an aniline substituted in the para position by --NHP(O)(OCH.sub.3).sub.2 and bearing an --H in the ortho position, and the acid addition salts thereof, have antitumor activity.

REFERENCES:
Cain et al., "J. Med. Chem", 18, 1110-1117 (1965).
Dobson et al., J. Chem. Soc., pp. 150-155, 1946.
Elslager et al., "J. Med. Pharm. Chem.", vol. 5, pp. 546-558, 1962.

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