1-1-Disubstituted-pen-2-em-3-carboxylic acids

Details 1-1-Disubstituted-pen-2-em-3-carboxylic acids 1-1-Disubstituted-pen-2-em-3-carboxylic acids

1979-12-03

1981-04-14

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

260239A, 2602452T, C07D48704, A61K 3140

Patent

active

042620112

ABSTRACT:
Disclosed are 1-substituted-pen-2-em-3-carboxylic acids (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics; such compounds are prepared by total synthesis. ##STR1## wherein R.sup.1 and R.sup.2 are, inter alia, substituted and unsubstituted alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, and spirocycloalkyl.

REFERENCES:
patent: 4181733 (1980-01-01), Christensen et al.
patent: 4206219 (1980-06-01), Christensen et al.
patent: 4208422 (1980-06-01), Christensen et al.

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