1,1-Diaryl-3-amino-prop-1-enes

Details 1,1-Diaryl-3-amino-prop-1-enes 1,1-Diaryl-3-amino-prop-1-enes

1975-09-29

1978-03-14

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260465G, 260465K, 2605011, 260544N, 260558R, 260562P, 260583E, 260591, 260645, 260646, 424304, 424316, 424330, C07C 8729

Patent

active

040790819

ABSTRACT:
3-Amino-prop-1-enes substituted in the 1-position by various specified combinations of phenyl, biphenylyl and fluorenyl groups and optionally substituted in the amino group by alkyl or benzyl groups, which have been found to be active against infections of Trypanosoma cruzi. Methods of making such compounds and pharmaceutical formulations containing the same.

REFERENCES:
patent: 2532292 (1950-12-01), Cusic
patent: 3375278 (1968-03-01), Moffett
patent: 3932663 (1976-01-01), Barrett
White et al., "Brit. Jour. Pharmaceutical", vol. 6, pp. 560-571, (1951).

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