1,1,3-Trisubstituted hydroxyguanidines

Details 1,1,3-Trisubstituted hydroxyguanidines 1,1,3-Trisubstituted hydroxyguanidines

1974-12-17

1976-12-28

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260556AR, 260556B, 260556S, 260558S, 2603977R, 260558A, 260559T, 260559S, 260559A, C07C13310

Patent

active

040001962

ABSTRACT:
Certain 1,1,3-trisubstituted hydroxyguanidines are useful intermediates in the preparation of 2-hydroxyguanidine O-carbamates which are antihypertensive agents. The intermediates are additionally useful as metal chelating agents and as antidepressant agents. Exemplary is 1-phenyl-1,3-dimethyl-2-hydroxyguanidine.

REFERENCES:
german Offenlegungsschrift, 2,040,628 (2/24/72).
Belzecki et al., Bull. Acad. Polo. Des Sciences, vol. 18, pp. 569-572 (1970).
Belzecki et al., J. Chem. Soc. Chem. Comm., pp. 806-807 (1970).
Braun et al., Ber. vol. 36, pp. 3660-3663 (1903).

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