1,1,2-triphenylbut-1-ene derivatives for treating Alzheimer's di

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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A61K 31135

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active

057191913

ABSTRACT:
The present invention provides novel methods of inhibiting Alzheimer's Disease comprising administering to a human in need of treatment an effective amount of a compound of formula I ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different provided that, when R.sup.1 and R.sup.2 are the same, each is a methyl or ethyl group, and, when R.sup.1 and R.sup.2 are different, one of them is a methyl or ethyl group and the other is hydrogen or a benzyl group; or a pharmaceutically acceptable salt thereof.

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Honjo, H., et al., "Senile Dementia-Alzheimer's Type and Estrogen," Morm. metab. Res. 27 (1995) 204-207.

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