Metal working – Method of mechanical manufacture – Prime mover or fluid pump making
Patent
1995-05-26
1997-10-21
Thorpe, Timothy
Metal working
Method of mechanical manufacture
Prime mover or fluid pump making
29888021, 2988802, 415900, 4174231, F04B 1703
Patent
active
056783060
ABSTRACT:
Methods are provided for minimizing damage to blood in a blood pump wherein the blood pump comprises a plurality of pump components that may affect blood damage such as clearance between pump blades and housing, number of impeller blades, rounded or flat blade edges, variations in entrance angles of blades, impeller length, and the like. The process comprises selecting a plurality of pump components believed to affect blood damage such as those listed hereinbefore. Construction variations for each of the plurality of pump components are then selected. The pump components and variations are preferably listed in a matrix for easy visual comparison of test results. Blood is circulated through a pump configuration to test each variation of each pump component. After each test, total blood damage is determined for the blood pump. Preferably each pump component variation is tested at least three times to provide statistical results and check consistency of results. The least hemolytic variation for each pump component is preferably selected as an optimized component. If no statistical difference as to blood damage is produced for a variation of a pump component, then the variation that provides preferred hydrodynamic performance is selected. To compare the variation of pump components such as impeller and stator blade geometries, the preferred embodiment of the invention uses a stereolithography technique for realizing complex shapes within a short time period.
REFERENCES:
patent: 4169990 (1979-10-01), Lerdman
patent: 4397049 (1983-08-01), Robinson et al.
patent: 4403177 (1983-09-01), Weber et al.
patent: 4546293 (1985-10-01), Peterson et al.
patent: 4662358 (1987-05-01), Farrar et al.
patent: 4712648 (1987-12-01), Mattes et al.
patent: 4846152 (1989-07-01), Wampler et al.
patent: 4984972 (1991-01-01), Clausen et al.
patent: 5040944 (1991-08-01), Cook
patent: 5112292 (1992-05-01), Hwang et al.
patent: 5135483 (1992-08-01), Wagner et al.
patent: 5174726 (1992-12-01), Findlay
patent: 5205721 (1993-04-01), Isaacson
patent: 5209650 (1993-05-01), Lemieux
patent: 5211546 (1993-05-01), Isaacson et al.
patent: 5258696 (1993-11-01), Le
patent: 5290227 (1994-03-01), Pasque
patent: 5321342 (1994-06-01), Kruse
patent: 5360317 (1994-11-01), Clausen et al.
patent: 5368438 (1994-11-01), Raible
patent: 5370509 (1994-12-01), Golding et al.
"A New Impeller Blood Pump Design In-Vitro and In-Vivo Studies;" by Qian et al. Perfusion; 1988; pp. 233-240.
"Low Hemolysis Pulsatile Impeller Pump Design Concepts and Experimental Results;" by Qian K; Journal of Biomedical Engineering; 1989; pp. 478-481.
"Development of Pulsatile Implantable Impeller Pump with Low Hemolysis;" by Qian et al.; China Journal of Biomedical Engineering; 1990; pp. 113-119.
Aber Gregory S.
Akkerman James W.
Bacak James W.
Benkowski Robert J.
Bozeman, Jr. Richard J.
Barr Hardie R.
Korytnyk Peter G.
The United States of America as represented by the Administrator
Thorpe Timothy
LandOfFree
Method for reducing pumping damage to blood does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for reducing pumping damage to blood, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for reducing pumping damage to blood will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-997554