HLDAT86 polynucleotides

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 4352523, 4352542, 435348, 435325, 536 231, C12P 2106, C12N 1500, C12N 120, C12N 506, C07H 2102

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active

061657514

ABSTRACT:
HLDAT86 (Wnt-4) polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HLDAT86 (Wnt-4) polypeptides and polynucleotides in the design of protocols for the treatment of kidney disorders, cancer, cardiac and vascular disease, inflammatory disorders, Alzheimers disease, schizophrenia and mood disorders., among others, and diagnostic assays for such conditions.

REFERENCES:
Cunningham, B.C., and Wells, A.P., Science 244: 1081-1085, 1992.
Nusse, R. and Varmus, H.E., Cell 69: 1073-1087, 1992.
Molecular Cell Biology, Darnell, Lodish, and Baltimore, Scientific American Books, Inc. p. 373, 1986.
Gavin, B.J. et al. Genes Dev. 4: 2319-2332, 1990.
Gavin, B.J. and McMahon, A.P. Mol. Cell. Biol. 12 (5): 2418-2423.
Hugue et al. "Differential Expression of Human Wnt Genes 2, 3, 4 and 7B in Human Breast Cell Lines And Normal and Disease States of Human Breast Tissue", Cancer Research vol.54(10) pages 2615-2621 (1994).

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