Methods and compositions for optimization of oxygen transport by

Details Methods and compositions for optimization of oxygen transport by Methods and compositions for optimization of oxygen transport by

1998-02-27

2000-04-25

Low, Christopher S. F.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 514832, 514833, 530385, 530402, 530813, 530815, 530829, 424529, A61K 3816, A61K 3514

Patent

active

060544279

ABSTRACT:
Compositions, and methods of use thereof, for use as blood substitute products comprise aqueous mixtures of oxygen-carrying and non-oxygen carrying plasma expanders and methods for the use thereof. The oxygen-carrying component may consist of any hemoglobin-based oxygen carrier, while the non-oxygen carrying plasma expander my consist of any suitable diluent.

REFERENCES:
patent: 3925344 (1975-12-01), Mazur
patent: 3956259 (1976-05-01), Garcia et al.
patent: 4001200 (1977-01-01), Bonsen et al.
patent: 4001401 (1977-01-01), Bonsen et al.
patent: 4053590 (1977-10-01), Bonsen et al.
patent: 4061736 (1977-12-01), Morris et al.
patent: 4133874 (1979-01-01), Miller et al.
patent: 4179337 (1979-12-01), Davis et al.
patent: 4301144 (1981-11-01), Iwashita et al.
patent: 4316093 (1982-02-01), Broers et al.
patent: 4336248 (1982-06-01), Bonhard et al.
patent: 4377512 (1983-03-01), Ajisaka et al.
patent: 4401652 (1983-08-01), Simmonds et al.
patent: 4412989 (1983-11-01), Iwashita et al.
patent: 4439357 (1984-03-01), Bonhard et al.
patent: 4473494 (1984-09-01), Tye
patent: 4473496 (1984-09-01), Scannon
patent: 4526715 (1985-07-01), Kothe et al.
patent: 4529719 (1985-07-01), Tye
patent: 4532130 (1985-07-01), Djordjevich et al.
patent: 4584130 (1986-04-01), Bucci et al.
patent: 4598064 (1986-07-01), Walder
patent: 4600531 (1986-07-01), Walder
patent: 4710488 (1987-12-01), Wong
patent: 4730936 (1988-03-01), Thorjusen, Jr.
patent: 4777244 (1988-10-01), Bonhard et al.
patent: 4826811 (1989-05-01), Sehgal et al.
patent: 4831012 (1989-05-01), Estep
patent: 4857636 (1989-08-01), Hsia
patent: 4861867 (1989-08-01), Estep
patent: 4911929 (1990-03-01), Farmer et al.
patent: 4987154 (1991-01-01), Long, Jr.
patent: 5028588 (1991-07-01), Hoffman et al.
patent: 5041615 (1991-08-01), Hai et al.
patent: 5061688 (1991-10-01), Beissinger et al.
patent: 5077036 (1991-12-01), Long, Jr.
patent: 5080885 (1992-01-01), Long, Jr.
patent: 5084558 (1992-01-01), Rausch et al.
patent: 5114932 (1992-05-01), Runge
patent: 5115100 (1992-05-01), Wu et al.
patent: 5128452 (1992-07-01), Hai et al.
patent: 5194590 (1993-03-01), Sehgal et al.
patent: 5200323 (1993-04-01), Chang et al.
patent: 5217648 (1993-06-01), Beissinger et al.
patent: 5234903 (1993-08-01), Nho et al.
patent: 5239061 (1993-08-01), Fronticelli et al.
patent: 5250665 (1993-10-01), Kluger et al.
patent: 5264555 (1993-11-01), Shorr et al.
patent: 5281579 (1994-01-01), Estep
patent: 5295944 (1994-03-01), Teicher et al.
patent: 5296465 (1994-03-01), Rausch et al.
patent: 5312808 (1994-05-01), Shorr et al.
patent: 5334705 (1994-08-01), Bonaventura et al.
patent: 5334706 (1994-08-01), Przybelski
patent: 5344393 (1994-09-01), Roth et al.
patent: 5349054 (1994-09-01), Bonaventura et al.
patent: 5352773 (1994-10-01), Kandler et al.
patent: 5386014 (1995-01-01), Nho et al.
patent: 5407428 (1995-04-01), Segall et al.
patent: 5438041 (1995-08-01), Zheng et al.
patent: 5439591 (1995-08-01), Pliura et al.
patent: 5449759 (1995-09-01), Hoffman et al.
patent: 5451205 (1995-09-01), Roth et al.
patent: 5464814 (1995-11-01), Sehgal et al.
patent: 5478805 (1995-12-01), Shorr et al.
patent: 5478806 (1995-12-01), Nho
patent: 5480866 (1996-01-01), Bonaventura et al.
patent: 5510464 (1996-04-01), Przybelski
patent: 5525630 (1996-06-01), Hoffman
patent: 5532352 (1996-07-01), Pliura et al.
patent: 5545328 (1996-08-01), Pliura et al.
patent: 5545727 (1996-08-01), Hoffman et al.
patent: 5554638 (1996-09-01), Dewhirst et al.
patent: 5563254 (1996-10-01), Hoffman et al.
patent: 5571801 (1996-11-01), Segall et al.
patent: 5574019 (1996-11-01), Segall et al.
patent: 5578564 (1996-11-01), Chivers et al.
patent: 5591710 (1997-01-01), Hsia
patent: 5595723 (1997-01-01), Quay
patent: 5599907 (1997-02-01), Anderson et al.
patent: 5613944 (1997-03-01), Segall et al.
patent: 5614490 (1997-03-01), Przybelski
patent: 5618919 (1997-04-01), Rausch et al.
patent: 5628930 (1997-05-01), Weers et al.
patent: 5631219 (1997-05-01), Rosenthal et al.
patent: 5635538 (1997-06-01), Weers et al.
patent: 5635539 (1997-06-01), Clark, Jr. et al.
patent: 5650388 (1997-07-01), Shorr et al.
patent: 5814601 (1998-09-01), Winslow
Mirhashemi et al., "Model analysis of the enhancement of tissue oxygenation by hemodilution due to increased microvascular flow velocity," Microvasc. Res. 34:290-301 (1987).
Mirhashemi et al., "Effects of hemodilution on skin microcirculation," Am. J. Physiol. 254:H411-H416 (1988).
Tsai and Intaglietta, "Local tissue oxygenation by statistically distributed sources," Microvasc. Res. 44:200-213 (1992).
Tsai et al., "Microcirculatory consequences of blood substitution with .alpha. .alpha. -hemoglobin," in Winslow et al., (eds.), Blood Substitutes. Physiological Basis of Efficacy, Birkhauser, Boston, MA, pp. 155-174 (1995).
Stetter et al., "Influence of a Recombinant Hemoglobin Solution on Blood Rheology," Transfusion 37:1149-1155 (1997).
Iwasaki and Iwashita, "Preparation and Evaluation of Hemoglobin-Polyethylene Glycol Conjugate (Pyridoxalated Polyethylene Glycol Hemoglobin) as an Oxygen-Carrying Resuscitaion Fluid," Artif. Organs 10:411-416 (1986).
Intaglietta, "Whitaker Lecture 1996: Microcirculation, Biomedical Engineering, and Artificial Blood," Ann. Biomed. Engineer. 25:593-603 (1997).
Simoni et al., "An Improved Blood Substitute," In Vivo Evaluation of its Hemodynamic Effects, ASAIO J., 42:M773-782 (1996).

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