Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivati

Details Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivati Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivati

1994-08-26

1995-12-19

Kunz, Gary L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2853, C07H 100, C07H 19067

Patent

active

054769329

ABSTRACT:
A process for preparing N4-acyl-5'-deoxy-5-fluorocytidine derivatives of formula III: ##STR1## by selective deacylation, wherein R is alkyl, cycloalkyl, alkenyl, aralkyl or aryl,
which comprises reacting a compound of formula II, ##STR2## wherein R is as defined above, with a base in an aqueous or inert organic solvent.

REFERENCES:
patent: 4966891 (1990-10-01), Fujiu et al.
Ninomiya et al, Jpn. J. Cancer Res. 81: 188-195, 1990.
Bloom et al. Nucl. Acids Res. 4(4): 1047-1063, 1977.

Affiliated with

Also associated with

Rating

Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivati does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivati, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivati will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-992729