Novel monoclonal antibodies

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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43524026, C07K 1300, C12N 500

Patent

active

050576046

ABSTRACT:
A monoclonal antibody which specifically reconizes a receptor that binds to proteins that contain the amino acid sequence Arg-Gly-Asp which on binding said proteins causes the cells to become substantially more phagocytic.

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Ginsberg et al., Thromb. Hemostasis, 59, 1-6 (1988).
Anderson & Springer, Ann. Rev. Med. 38, 175-194 (1987).
Brown & Goodwin, J. Exp. Med. 167, 777-793 (1988).
Wright & Meyer, J. Exp. Med. 162, 762-767 (1985).
Pierschbacher, Science, 238, 491-497 (1987).

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