Pharmaceutical preparations

Details Pharmaceutical preparations Pharmaceutical preparations

1990-05-24

1991-10-15

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514269, 514936, 514937, 514970, 514975, 544242, 544312, 544313, 544315, 544317, 544406, 546265, 546276, 546294, 546341, 546347, 546348, 548178, 548202, 548325, 548347, 548356, 364291, 364294, A61K 31505, C07D23900, C07D23902, C07D21170

Patent

active

050575180

ABSTRACT:
The synthesis and application of N(1)-n-alkyl-pyrimidinium-salts are described. These surfactants have a very small critical micelle concentration (CMC) in the order of 10.sup.-5 -10.sup.-7 Mol/Liter. These N(1)-n-alkyl-pyrimidinium components have pharmacological activities and can act as antimetabolites.

REFERENCES:
F. J. Fendler et al., J. Chem. Soc., Perkin III, 1097 (1977).
Attwood, D. et al., J. Phys. Chem., 74, 3529 (1970).
Mittal, K. L., Micellization, Solubilization and Microemulsions, Plenum Press, New York (1977).
Mittal, K. L., Solution Chemistry of Surfactants, Plenum Press, New York (1979).

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