Methods of improving peak resolution in reversed-phase electroch

Liquid purification or separation – Processes – Chromatography

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2101982, 210748, 204542, 204545, 204551, B01D 1508

Patent

active

060540532

ABSTRACT:
Peak resolution in reversed-phase electrochromatography is improved in either of two alternative ways. The first is by a stepwise increase in the concentration of acetonitrile or other equivalent buffer constituent or modifier after the sample has been loaded, and the second is the inclusion of a surfactant in the mobile phase.

REFERENCES:
patent: 4315812 (1982-02-01), Karlson
patent: 4683042 (1987-07-01), Scott
patent: 5453382 (1995-09-01), Novotney
patent: 5611904 (1997-03-01), Cole
patent: 5647979 (1997-07-01), Liao

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