Pasteurella haemolytica leukotoxin compositions and uses thereof

Details Pasteurella haemolytica leukotoxin compositions and uses thereof Pasteurella haemolytica leukotoxin compositions and uses thereof

1993-02-09

1995-12-19

Sidberry, Hazel F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

530350, 5303881, 435 691, 4241851, 4242551, 4242821, A61K 3900, A61K 39102, A61K 4500, C07K 1504

Patent

active

054766575

ABSTRACT:
New proteins and subunit antigens from P. haemolytica for use in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The subunit antigens include immunogenic amino acid sequences of P. haemolytica fimbrial protein, P. haemolytica plasmin receptor protein, and P. haemolytica 50K outer membrane protein and P. haemolytica leukotoxin. The antigens can be used in a vaccine composition, either alone or in combination. Also disclosed are methods of vaccination as well as methods of making the subunit antigens employed in the vaccines.

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