Treatment of inflammatory diseases of the mammalian large intest

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424305, A61K 3119, A61K 31215

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active

040839982

ABSTRACT:
The present invention provides a method for treatment or prophylaxis of certain inflammatory diseases of the mammalian large intestine which comprises administrating a cytoprotective prostaglandin to a mammal who suffers from or is particularly susceptible to said inflammatory diseases of the large intestine. Cytoprotective prostaglandins refer to those prostaglandin-type compounds which are useful in reducing the incidence of NOSAC-induced lesions in the intestinal wall of the rat. "NOSAC" is an abbreviation for "nonsteroidal antiinflammatory compound. "

REFERENCES:
patent: 3903297 (1975-09-01), Robert
patent: 3911124 (1975-10-01), Robert
patent: 3917828 (1975-11-01), Robert

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