Method of inhibiting replication of HIV with water-soluble melan

Details Method of inhibiting replication of HIV with water-soluble melan Method of inhibiting replication of HIV with water-soluble melan

1990-03-20

1991-10-15

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Separated animal oil or solidified form thereof derived from...

514 2, 514885, A01N 3718, A61K 3702

Patent

active

050573250

ABSTRACT:
Replication of human immunodeficiency virus (HIV) is inhibited in human patients by administering melanins. L-dopa melanin is preferred, but other water-soluble melanins can be used.

REFERENCES:
Blois, "The Melanins: Their Synthesis and Structure", Photochemical and Photobiological Reviews, vol. 3, pp. 115-135, 1978.
Debing et al., "Melanosome Binding and Oxidation-Reduction Properties of Synthetic L-DOPA-Melanin as in vitro Tests for Drug Toxicity", Molecular Pharmacology, 33: 470-476, Jan. 1988.

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