Slow-release pharmaceutical agent

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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Details

424461, 424470, 424472, 424474, 424480, 424490, 424499, A61K 900, A61K 924, A61K 926, A61K 954

Patent

active

050573179

ABSTRACT:
Slow-release pharmaceutical agents which comprise at least one adenine, cystine and tyrosine in combination with at least one pharmaecutically active substance are disclosed. The slow-release pharmaceutical agents which may be tablet, granule, implant, capsule, troche, etc., can either slowly release their active substances over time or release the active substances a predetermined time after their administration. And the slow-release pharmaceutical agent may be used with practically all types of drugs irrespective of whether they are water-soluble or slightly water-soluble, including hypotensives, antipyretic analgesic antiinflammatories, immunoregulators, adrenocortical hormones, antidiabetic agent, vasodilators, cardiotonics, antiarrhythmic agents, anti-arteriosclerotic agents, and antidotes.

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M. Nakano et al., J. Pharm. Sci., 72, 378, 1983 "Sustained Release of Theophylline from Hydroxypropylcellulose Tablets".
G. Kallstrand et al., J. Pharm. Sci., 72, 772, 1983 "Membrane-Coated Tablets: A System for the Controlled Release of Drugs".
S. S. Jambhekar et al., J. Pharm. Sci., 74, 991, 1985 "pH-and Flow-Rate-Independent Release of Drug from Uncoated Slow-Release Tablets".

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