Transdermal hormone replacement therapy

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

Patent

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Details

Other Related Categories

514170, A61K 31565, A61K 3157, A61K 3158, A61L 1503

Type

Patent

Status

active

Patent number

054221196

Description

ABSTRACT:
The present invention provides a method of treating a female in need of hormone replacement therapy comprising transdermally administering to said female a series of alternating phases of from about one to about four days of estrogen dominant activity and phases of from about one to about four days of progestin dominant activity, with the estrogen dominant activity phase consisting of administering a transdermal estrogen substance alone or administering a transdermal estrogen substance and a transdermal progestin substance and the progestin dominant activity phase consisting of administering a transdermal progestin substance and a transdermal estrogen substance, the amount of progestin substance being alternately increased in the progestin dominant activity phase and decreased in the estrogen dominant activity phase to provide the required dominant activity.

REFERENCES:
patent: 5108995 (1992-04-01), Casper
patent: 5256421 (1993-10-01), Casper

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