Transdermal administration of amines with minimal irritation and

Details Transdermal administration of amines with minimal irritation and Transdermal administration of amines with minimal irritation and

1992-09-21

1995-06-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

514947, A61F 1300, A61K 908, A61K 3113

Patent

active

054221188

ABSTRACT:
An effective amount of a skin irritating physiologically active amine can be transdermally or topically administered in a minimally or nonirritating composition that maintains a suitably high transdermal flux rate, by providing the amine as a minimally or nonirritating salt of a stoichiometric molar excess of a fatty acid of from 8 to 20 or 22 carbon atoms, in a nonpolar, nonvolatile solvent.

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