Spectral diagnosis of diseased tissue

Surgery – Truss – Pad

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61B 600

Patent

active

054213371

ABSTRACT:
The present invention relates to a method and apparatus for diagnosing the condition of gastrointestinal tissue. The method and apparatus excite fluorophores within a portion of gastrointestinal tissue with a laser to cause the fluorophores to emit fluorescent radiation. The presence of abnormal tissue is then determined by detecting the radiation emitted by the excited fluorophores and comparing the emitted radiation to a reference emission for fluorophores within normal tissue at predetermined wavelengths.

REFERENCES:
patent: 3327119 (1967-06-01), Kamentsky
patent: 4556057 (1985-12-01), Hiruma et al.
patent: 4676231 (1987-06-01), Husazumi et al.
patent: 4693556 (1987-09-01), McCaughan, Jr.
patent: 4718417 (1988-01-01), Kittrell et al.
patent: 4768513 (1988-09-01), Suzuki
patent: 4773097 (1988-09-01), Suzaki et al.
patent: 4785806 (1988-11-01), Deckelbaum
patent: 4786813 (1988-11-01), Svanberg et al.
patent: 4930516 (1990-06-01), Alfano et al.
patent: 4957114 (1990-09-01), Zeng et al.
patent: 4981138 (1991-01-01), Deckelbaum et al.
patent: 5003977 (1991-04-01), Suzuki et al.
patent: 5201318 (1993-04-01), Rava et al.
patent: 5345941 (1994-09-01), Rava et al.
"Autofluorescence of Various Rodent Tissues and Human Skin Tumour Samples" Anderson et al.
"Immunofluorescence studies on the occurrence and localization of the CEA-related biliary glycoprotein I (BFP I) in normal human gastrointestinal tissues". Svenberg et al., Publication of Karolinska Hospital.
"Laser Induced Flourescence Studies of Hematoporphyrin Derivative (HPC) in Normal and Tumor Tissue of Rat", Ankerst et al., Applied Spectroscopy, vol. 38, No. 6, 1984 pp. 890-896.
"Tissue characterization using laser-induced fluorescence", Anderson et al. Tuesday Morning, Apr. 28 pp. 46-48.
"Contrast enhancement in tumor localization using hemotoporphyrin derivative laser-induced fluorescence", Ankerst et al., Friday Morning, Jun. 22 pp. 234-235.
"Multicolor Imaging and Contrast Enhancement in Cancer Tumor Localization using laser-induced fluorescence in hematoporphyrin derivative-bearing tissue", Montan et al., Wednesday Morning, May 22, pp. 82-84.
"Spectral Characteristics in Tissue Diagnostics using Laser-Induced Fluorescnece", Ankerst et al., ICALEO vol. 43, 1984, pp. 52-60.
"Multispectral System for Medical Fluorescence Imaging", Anderson et al., IEEE Journal of Quantum Electronics, vol. QE-23 No. 10, Oct. 1987, pp. 1798-1805.
"Fluorescence Studies of Hematoporphyrin Dirative in Normal and Malignant Rat Tissue", Svanberg et al., Cancer Research Aug. 1986 pp. 3803-3808.
"Spectral Studies of GI Tissues: Optimizing Excitation and Emission Wavelengths for Discrimination of Normal and Adenomatous Tissues", Kortum Abstract.
"Tumor Localization by Means of Laser-Induced Fluorescence in Hematoporphyrin Derivative (HPD)-Bearing Tusue", Anderson et al. Proceedings of the Seventh International Conference Laser Spectroscopy VII, Jun. 24-28 1985.
"Multicolor imaging and contrast enhancement in cancer-tumor localization using laser-induced fluorescence in hematopotphyrin-derivative-bearing tissue", Montan et al., Optics Letters, vol. 10 No. 2 Feb. 1985 pp. 56-58.
Alfano, Robert R., et al., "Laser Induced Fluorescence Spectroscopy from Native Cancerous and Normal tissue", Journal of Quantum Electronics, AE20 (12):1507-1511, Dec. (1984).
Dal Fante, Marco, et al., "Behaviour of Haematoporphyrin Derivative in Adenomas and Adenocarcinomas of the Colon: a Microfluorometric Study", Lasers in Medical Science, 3:165-171, (1988).
Kapadia, Cyrus R., et al., "Laser-Induced Fluorescence Spectroscopy of Human Colonic Mucosa, Detection of Adenomatous Transformation", Gastroenterology 99 (1): (1990).
Yuanlong, Yang, et al., "Characteristic Autofluorescence for Cancer Diagnosis and Its Origin", Lasers in Surgery and Medicine, 7:528-532 (1987).
Cothren, R. M., Ph.D., et al., "Gastrointestinal tissue diagnosis by laser-induced fluorescence spectroscopy at endoscopy", Gastrointenstinal Endoscopy, 36 (2): 105-111, (1990).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Spectral diagnosis of diseased tissue does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Spectral diagnosis of diseased tissue, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spectral diagnosis of diseased tissue will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-980202

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.