Method for selection of biologically active peptide sequences

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 5, 435 71, 435 72, 435 721, 435 73, 435 732, 435 737, 435 75, 435962, 436501, 436518, G12Q 164, G01N 3353

Type

Patent

Status

active

Patent number

057503443

Description

ABSTRACT:
An improved method for determining binding compounds from a mixture of similar compounds, particularly a phage peptide library, is provided. The method comprises contacting a mixture of candidate compounds with a target molecule presented on two or more different substrates.

REFERENCES:
Christian et al J. Mol. Biol. 227 pp. 711-718 (1992) "Simplified Methods for Construction, Assessment and Rapid Screening of Peptide Librerics in Bacteiophage".
Parmley et al Gene 73 pp. 305-318 (1988) "Antibody-Selectable Fila Mentous Fd Phage Vectors: Affinity Purification of Forget Genes".

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