Methods of detecting nucleic acids with nucleotide probes contai

Details Methods of detecting nucleic acids with nucleotide probes contai Methods of detecting nucleic acids with nucleotide probes contai

1995-05-02

1998-05-12

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 231, 536 243, 536 2432, 536 253, 536 2532, C07H 2104, C12Q 168

Patent

active

057503435

ABSTRACT:
This invention relates to use of oligonucleotides having at least one nucleotide that is substituted at the 4'-position of the sugar moiety with a substituent other than hydrogen as nucleotide probes in methods for detecting the presence or amount of a polynucleotide analyte in a sample suspected of containing the polynucleotide analyte. These oligonucleotides can also be packaged in diagnostic assay kits.

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