Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1982-06-25
1984-07-24
Phillips, Delbert R.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260112R, 424101, 424177, C07C10352, C07G 700, A61K 3514, A61K 3700
Patent
active
044617259
ABSTRACT:
The present invention is directed to certain multiprotein compounds and methods for using such compounds in the treatment of psoriasis, arthritis, erythropoietic protoporphyria, and scar tissue and wounds. These multiprotein compounds include beta-lactoglobulin, alpha-lactalbumin, and bacitracin. The beta-lactoglobulin proteins are linked to alpha-lactalbumin proteins by a plurality of organic linkages formed by reacting various alcohols, e.g., noncyclic alcohols, steroid alcohols, triterpenoid alcohols, and thioglycerol therewith. The alpha-lactalbumin proteins are linked to the bacitracin proteins by a plurality of organic linkages formed by reacting with fatty acids therewith. A selenium ion may be bonded to each bacitracin protein molecule of the multiprotein compounds. Additionally, pairs of bacitracin molecules may be linked by zinc ions or other cations, to form a salt with the bacitracin.
REFERENCES:
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Herbert S. Anker et al., "Bacitracin: Methods of Production, Concentration, and Partial Purification, with a Summary of the Chemical Properties of Crude Bacitracin," 55 Journal of Bacteriology 249-255 (1948).
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Hulse Dale E.
Jensen Allen R.
Phillips Delbert R.
Workman H. Ross
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