Method for chemical analysis

Chemistry: analytical and immunological testing – Optical result – With reagent in absorbent or bibulous substrate

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Details

436808, 422 56, 422 58, 422 61, G01N 3122

Patent

active

051734338

ABSTRACT:
A chemical analysis test device for detection of a selected chemical in a biological fluid is disclosed wherein the test is preformed on a rigid base containing a detection well for holding a reagent and a specimen well for holding a sample of the biological fluid to be tested. The detection well is positioned above a concentration chamber wherein the cross-sectional area of the chamber increases as the distance from the bottom of the detection well increases. A passage connects the concentration chamber to the detection well. The specimen well has a generally hemispherical interior surface and has an opening in the bottom thereof. A strip of wicking material is secured to the base interconnecting the opening in the specimen well and the concentration chamber. A specimen of the biological fluid to be tested is deposited in the specimen well and contacts the wicking material through the opening in the bottom of the well. The wicking paper wicks the specimen across to the concentration chamber and is treated with an agent to volatilize the chemical under test. The volatilized chemical is concentrated by the concentration chamber and forced through the passage into contact with the reagent stored in the detection well, producing a visible color change in the detection well above the passage, indicative of the chemical content in the biological fluid.

REFERENCES:
patent: 3582285 (1971-06-01), Hamilton
patent: 3888628 (1975-06-01), Graham
patent: 4154793 (1979-05-01), Guigan
patent: 4780280 (1988-10-01), Berger et al.
patent: 4789629 (1988-12-01), Baker et al.

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