Stable gas-carrying compositions

Details Stable gas-carrying compositions Stable gas-carrying compositions

1982-03-19

1984-07-24

Lovering, Richard D.

Compositions

Preservative agents

Anti-corrosion

252311, 252314, 424352, A61K 31025, B01J 1300

Patent

active

044617178

ABSTRACT:
Aqueous dispersions of a non-aromatizable perfluorinated C.sub.9 -C.sub.18 polycyclic hydrocarbon having gas carrying properties, and a minor amount of an amidoamine oxide surfactant, the dispersions having at room temperature an average particle size of not over 0.1 micron initially and less than 0.3 micron for up to about one year or more. The ability of the dispersions to maintain low particle size over long periods at room temperature indicates exceptional stability, making them valuable as blood substitutes and therapeutic agents.

REFERENCES:
patent: 3547995 (1970-12-01), Bartlett
patent: 3778381 (1973-12-01), Rosano et al.
patent: 3823091 (1974-07-01), Samejima et al.
patent: 3828085 (1974-08-01), Price et al.
patent: 3911138 (1975-10-01), Clark, Jr.
patent: 3962439 (1976-06-01), Yokoyama et al.
patent: 3993581 (1976-11-01), Yokoyama et al.
patent: 4041086 (1977-08-01), Moore et al.
patent: 4105798 (1978-08-01), Moore et al.
patent: 4220606 (1980-09-01), Moore
Derwent Abstract J55147218-Describes Japanese Patent Publication 80/147218, Nov., 17, 1980 based on Japanese Appl'n. 80/46582 filed Apr. 9, 1980.
Dagani: "Synthetic Blood Research Progressing", Chemical and Engineering News, May 3, 1982, pp. 31-33.

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