Nonaqueous fluorinated drug delivery vehicle suspensions

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424426, 424428, 424423, 424434, 424435, 424499, 424501, 424 7803, 424 7804, 424 7833, 514912, 514963, 514965, 523122, A61K 914, A61K 4734, A61K 4706, A61K 4732

Patent

active

051732980

ABSTRACT:
Nonaqueous pharmaceutical compositions for use in aqueous physiological systems are disclosed comprising drug delivery vehicles suspended in nonaqueous perfluorocarbon or fluorinated silicone liquid carriers. The suspended drug delivery vehicles may be water labile or water stable and incorporate therapeutic or diagnostic compounds which remain stable and pharmaceutically effective for extended periods. The pharmaceutical compositions possess extended shelf-lives and do not leach the incorporated therapeutic or diagnostic compounds into the liquid carriers making them well suited for multi-dose packaging and administration.

REFERENCES:
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patent: 4105798 (1978-08-01), Moore et al.
patent: 4115544 (1978-09-01), Shell
patent: 4366169 (1982-12-01), White
patent: 4452818 (1984-06-01), Haidt
patent: 4649047 (1987-03-01), Kaswan
patent: 4865846 (1989-09-01), Kaufman
patent: 4882150 (1989-11-01), Kaufman

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