Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1988-08-24
1990-10-09
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
552201, 514680, A61K 3165, C07C 49423, C07C 5036
Patent
active
049621254
ABSTRACT:
A novel physiologically active substance KS-619-1 having a vasodilative activity is produced by culturing Streptomyces californicus ATCC 3312.
REFERENCES:
Chemical Abstract, vol. 109(7) #53,205w, 1987, "Microbial production of vasodilator KS-169-1".
Chemical Abstract, vol. 107(23) #214020h, 1987, Structure of a novel calcium and calmodulin-dependent cyclic nucleotide phosphodieterase inhibitor KS-619-1.
Chemical Abstract, vo. 105(9) #59955, 1980, "Vasodilitor compound".
Chemical Abstract, vol. 107(21) #193918g, "KS--619--1 a new inhibitor of calcium and calmodulin", dep. cyc., nucleotide phosphodiesterase from Step. californicus.
Kase Hiroshi
Matauda Yuzuru
Shirahata Kunikatsu
Yamada Koji
Yasuzawa Toru
Covington Raymond
Kyowa Hakko Kogyo Co. Ltd.
Meller Michael N.
Raymond Richard L.
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