Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1978-01-17
1980-04-08
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424279, 424283, 424285, 424316, 424320, A61K 3119
Patent
active
041973160
ABSTRACT:
Preventive as well as therapeutic treatment to alleviate the symptoms of disorders characterized by cracking, flaking or scaling of the skin consisting of the topical application of a lotion, cream or ointment containing one or more of the .alpha.- or .beta.-hydroxy acids or .alpha.-keto acids and esters thereof, their amides and their ammonium salts is disclosed. The compounds include free acid, amide and/or ammonium salt forms of citric acid, glycolic acid, glucuronic acid, galacturonic acid, glucuronolactone, gluconolactone, .alpha.-hydroxybutyric acid, .alpha.-hydroxyisobutyric acid, lactic acid, malic acid, mandelic acid, mucic acid, pyruvic acid, methyl pyruvate, ethyl pyruvate, .beta.-phenyllactic acid, .beta.-phenylpyruvic acid, saccharic acid, tartaric acid, tartronic acid, and .beta.-hydroxybutyric acid. The therapeutic composition may include one or more of the compounds present in the total amount of from one to twenty percent. Topical application to affected areas has been found to achieve amelioration of the dry skin.
REFERENCES:
patent: 3096244 (1963-07-01), Ehrhart et al.
patent: 3124506 (1964-03-01), Holman
patent: 3879537 (1975-04-01), Scott et al.
patent: 3920835 (1975-11-01), Scott et al.
patent: 3984566 (1976-10-01), Scott et al.
patent: 3988470 (1976-10-01), Scott et al.
patent: 4021572 (1977-05-01), Scott et al.
Handbook of Non-Prescription Drugs, 5th ed., 1977, p. 325.
Scott Eugene J. Van
Yu Ruey J.
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