Chemistry: analytical and immunological testing – Composition for standardization – calibration – simulation,... – Particle count or volume standard or control
Patent
1985-05-17
1990-10-09
Wax, Robert A.
Chemistry: analytical and immunological testing
Composition for standardization, calibration, simulation,...
Particle count or volume standard or control
436 8, 436 17, 436 18, 2524081, G01N 3100
Patent
active
049620380
ABSTRACT:
An isotonic multipurpose blood diluent, and a method for use of this diluent with a weak lysing reagent system which is especially suitable for routine enumeration of traditional hemogram values, and also the determination of lymphoid-myeloid populations of leukocytes, particularly in automatic particle counting systems.
This blood diluent is capable of affording accurate, reproducible test results. It is an osmotically balanced aqueous solution of preselected pH containing Procaine hydrochloride for maintaining erythrocyte morphology during operation, N-(2-acetamido)iminodiacetic acid (ADA) as a blood cell stabilizing agent, and bacteriostatic agents including sodium 1-hydroxypyridine-2-thione, and dimethylolurea which, together with the ADA, allow preferential determination of myeloid-lymphoid leukocytes, and other hematological values.
The lysing agent is a mixture of an aqueous solution of at least one quaternary ammonium salt having surface active properties, and an alkali metal cyanide.
REFERENCES:
patent: 2745826 (1956-05-01), Semenoff et al.
patent: 3281366 (1966-10-01), Judge et al.
patent: 3874852 (1975-04-01), Hamill
patent: 3962125 (1976-06-01), Armstrong
patent: 4102810 (1978-07-01), Armstrong
patent: 4116635 (1978-09-01), Jaegar
patent: 4185964 (1980-01-01), Lancaster
patent: 4213876 (1980-07-01), Crews et al.
patent: 4219440 (1980-08-01), Runck et al.
patent: 4248634 (1981-02-01), Forester
patent: 4286963 (1981-09-01), Ledis et al.
patent: 4346018 (1981-08-01), Carter et al.
patent: 4485175 (1984-11-01), Ledis et al.
patent: 4528274 (1985-07-01), Carter et al.
patent: 4529705 (1985-07-01), Larsen
patent: 4617275 (1986-10-01), Matsuda et al.
Nicol, D. H. et al., J. Clin. Path. (1971) 24, p. 882.
Davis, R. E. et al., J. Jed. Lab. Technol. (1969) 26, pp. 26-30.
Barnard, D. E. et al., J. Clin. Path., 22, Suppl. Coll. Path. (1969) 3, pp. 26-30
Ballard, B. C. D., J. Clin. Path., 25, p. 460 (1972).
Hatch et al., Am. J. Clin. Path., 36, pp. 220-223 (1961).
Armak Arquad C-50 Bulletin.
J. M. England et al., Lancet, Mar. 1, 1975, p. 492.
J. M. England et al., Lancet, May 22, 1976, p. 1143.
J. M. England et al., J. Clin. Path., 27, p. 623 (1974).
P. A. Wycherly and M. J. O'Shea, J. Clin. Path., 31, p. 271 (1978).
D'Angelo et al., J. Clin. Path., 38, No. 6, pp. 658-662.
W. E. Love, J. Cell. and Comp. Physiol., 44, pp. 291-313 (1954).
"Hackh's Chemical Dictionary", McGraw Hill, Grant, 3rd Edition, p. 707.
"Chemistry of Organic Compounds", Sanders, Noller, 2nd Edition, 1957, pp. 241 and 243.
Carter James H.
Crews Harold R.
Ledis Stephen L.
Coulter Electronics Inc.
Hibnick Gerald R.
Sparks Meredith P.
Wallen T. J.
Wax Robert A.
LandOfFree
Multi-purpose blood diluent and lysing agent for differential de does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Multi-purpose blood diluent and lysing agent for differential de, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Multi-purpose blood diluent and lysing agent for differential de will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-973106