Leukotriene-B.sub.4 derivatives, process for their production an

Details Leukotriene-B.sub.4 derivatives, process for their production an Leukotriene-B.sub.4 derivatives, process for their production an

1993-12-03

1995-08-08

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546309, 546314, 546323, 546340, 546341, 546344, 562470, C07D21360, C07C 5948

Patent

active

054400449

ABSTRACT:
The present invention relates to a leukotriene-B.sub.4 analog according to formula I ##STR1## in which R.sup.1 is a COOR.sup.2 group, wherein R.sup.2 is a C.sub.2-4 -alkyl group;

REFERENCES:
Lin et al., "Novel Molecules that Antagonize Leucotriene B4 Binding to Neutrophils," Ann. N.Y. Acad. Sci., vol. 524, pp. 196-200 (Apr. 9, 1988).
Chemical Abstracts 112:55263z (Feb. 19, 1990).
Morris et al., "Synthesis of Novel Antagonists of Leukotriene B4," Tetrahedron Letters, vol. 29, No. 2, pp. 143-146 (Jan. 1988).
Burgos et al., "Asymmetric Synthesis of the Diastereoisomers of the Leukotriene B4 Antagonist," Tetrahedron Letters, vol. 30, No. 38, pp. 5081-5084 (Oct. 1989).
Chem. Abstr. 110(19):172989k; J. Morris; Jul. 14, 1988 PCT; 1989.

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