Thioheterocyclic near-infrared dyes

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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544298, 544316, 544318, 544345, 548142, 548159, 548221, 548251, 5482632, 5482634, 5482648, 548427, 548465, C07D23938, C07D26358, C07D25704, C07D24912

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054400422

ABSTRACT:
Disclosed is a novel near-infrared absorbing dye of formula: ##STR1## wherein X.sup.1, X.sup.2 independently represents --CR.sup.8 R.sup.9 --, --S--, --Se--, --NR.sup.10 --, --CH.dbd.CH-- or --O--;

REFERENCES:
patent: 4882265 (1989-11-01), Laganis et al.
Synthetic Communications, 22(17) 2593-2598 (1992) Facile Derivatizations of Heptamethine Cyanine Dyes--Sucjan Strekowski et al.--Dept of Chemistry, Georgia State University.
American Chemical Society, pp. 4578-4580M16 (1992) Substitution Reactions of a Nucleofugal Group in Heptamethine Cyanine Dyes. Synthesis of an Isothiocycano Derivative for Labeling of Proteins with a Near--Infrared Chromophore. J. Org. Chem. 57, 4578-80, 1992.
Williams et al., Anal. Chem., 65, 601-605, Mar. 1993.

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