Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1987-11-19
1990-10-09
Draper, Garnette
Drug, bio-affecting and body treating compositions
Lymphokine
424 11, 424 9, 514 2, 514 8, 514 21, 514917, 514922, 600 1, A61K 3702, A61M 3600
Patent
active
049619268
ABSTRACT:
This invention provides method of preventing mucositis in a subject susceptible to mucositis comprising administering to the subject a prophylactically effective amount of granulocyte colony stimulating factor or a polypeptide analog thereof having substantially the same amino acid sequence and the activity of naturally occurring granulocyte colony stimulating factor. This invention further provides a method of treating mucositis in a subject having mucositis comprising administering to the subject a therapeutically effective amount of granulocyte colony stimulating factor or a polypeptide analog thereof having substantially the same amino acid sequence and the activity of naturally occurring granulocyte colony stimulating factor.
REFERENCES:
Moore et al. PNAS 84, 1987, pp. 7134-7138.
Matsumata et al., Inf and Inn 55(11) 1987, pp. 2715-2720.
Chirigos et al., "Cancer Detection and Prevention" Suppl 1, 1987, pp. 385-387.
J. Clin Invest, Supp; 1987, vol. 79, pp. 1549-1557.
Henderson, Drug and Hemabologic Reacton, Ed Gruve, 1974, pp. 207-221.
Pizzo, P. A. and Young, R. C., "Infections in the Cancer Patient," in Cancer Principles and Practices of Oncology, DeVita, et al., Eds., pp. 1963-1998 (1985).
DeVita, V. T., Journal of Clinical Oncology, vol. 4, pp. 1157-1159 (1986).
Souza, L. M., et al., Sciences, vol. 232, pp. 61-65 (1986).
Welte, K., et al., Journal of Exp. Medicine, vol. 165, pp. 941-948 (1987).
Welte, K., et al., Experimental Hematology (ISEH), vol. 16, p. 72 (1987).
Sternberg, C. N., et al., Journal of Urology, vol. 133, pp. 403-407 (1985).
Blum, R. H., et al., "Principles of Dose, Schedule, and Combination Chemotherapy", in Cancer Medicine, Holland J. and Frei, E. III, Eds., Lea and Febiger, Philadelphia, pp. 730-752 (1982).
Draper Garnette
Sloan-Kettering Institute for Cancer Research
White John P.
LandOfFree
Methods for prevention and treatment of mucositis with granulocy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for prevention and treatment of mucositis with granulocy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for prevention and treatment of mucositis with granulocy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-972337