Piperidyl-substituted indoles for treating anxiety

Details Piperidyl-substituted indoles for treating anxiety Piperidyl-substituted indoles for treating anxiety

1992-12-17

1995-08-08

Chang, Ceila

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514256, 514316, 514318, 514324, 514339, 546193, 546201, 546256, 546257, 546262, 546273, 544335, A61K 31445, C07D40114, C07D40314, C07D40304

Patent

active

054399220

ABSTRACT:
A method for treating anxiety in mammals comprising administering in an effective amount to said mammal an 1-aryl-3-(4-piperidyl)-indole derivative having the general formula: ##STR1## wherein R.sup.1 is H, F, Cl, Br, methyl, methoxy or cyano; and R.sup.3 is H or methyl; or a pharmaceutical acceptable acid addition salt thereof.

REFERENCES:
patent: 4710500 (1987-12-01), Perregaard
patent: 4997841 (1991-05-01), Oxford
patent: 5036078 (1991-07-01), Coates
patent: 5216001 (1993-06-01), Perregaard
Skarsfeldt et al., "Sertindole, a new neuroleptic . . . ", CA 113:109264s (1990).
Ueda et al., "Preparation of (piperidinoalkyl)thiazoles as antiallergy agents", CA 107:236692f (1987).

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