Certain 4-(3,4-dibromocyclohexyl)pyridines

Details Certain 4-(3,4-dibromocyclohexyl)pyridines Certain 4-(3,4-dibromocyclohexyl)pyridines

1985-03-25

1986-08-05

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546156, 546329, C07D21326

Patent

active

046044671

ABSTRACT:
A 4-cyclohexenylpyridine is brominatively aromatized to the corresponding 4-phenylpyridine by brominating the cyclohexenylpyridine, such as a 4-(halocyclohexenyl)pyridine, especially a 4-(4-halocyclohex-3-enyl)pyridine hydrohalide, and heating the brominated product in an inert solvent and in the presence of a base to form, e.g., a 4-(halophenyl)pyridine. The invention is of particular utility in the manufacture of intermediates of antibacterial 1-alkyl- 1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acids.

REFERENCES:
patent: 4405792 (1983-09-01), Walter

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