Hydroxamates

Details Hydroxamates Hydroxamates

1985-04-04

1986-08-05

Evans, J. E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

260404, 2604045, 2605005H, 2605011, 26050111, 514555, 560 20, 560312, 562452, A61K 31165, A61K 31185, C07C 8310

Patent

active

046044078

ABSTRACT:
Hydroxamates are provided having the structure ##STR1## wherein R.sup.1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, or ##STR2## wherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C.sub.1 -C.sub.4 -alkylamino or C.sub.1 -C.sub.4 -dialkylamino.

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Corey et al., "Rationally Designed, Potent Competitive Inhibitors of Leukotriene Biosynthesis", J. Am. Chem. Soc., 1984, 106, 1503-1504.

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