Perfluoro-1-azatricyclic amine compounds useful as oxygen carrie

Details Perfluoro-1-azatricyclic amine compounds useful as oxygen carrie Perfluoro-1-azatricyclic amine compounds useful as oxygen carrie

1985-07-05

1986-08-05

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514214, 514832, 514833, 540477, 540581, A61K 31395, A61K 3155, C07D48708

Patent

active

046043853

ABSTRACT:
A novel compound of the formula, ##STR1## wherein k is zero or an integer of 1 to 2, j is an integer of from 1 or 3, l and m are each zero or an integer of from 1 to 3, and n is an integer of from 1 to 4, the rings A, B and C being optionally substituted with at least one trifluoromethyl group or tetrafluoroethyl group is prepared by reacting the perhydro compound corresponding thereto with fluorine. The compound is useful as a material capable of carrying oxygen in an aqueous emulsion for lifesaving a patient suffering from massive hemorrhage and for preserving internal organs in transplantation.

REFERENCES:
patent: 4186253 (1980-01-01), Yokoyama et al.
patent: 4425347 (1984-01-01), Yokoyama et al.
patent: 4526969 (1985-07-01), Yokoyama et al.
patent: 4562183 (1985-12-01), Tatlow et al.

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